WebMar 21, 2024 · RPTOR (Regulatory Associated Protein Of MTOR Complex 1) is a Protein Coding gene. Diseases associated with RPTOR include Tuberous Sclerosis and Subependymal Glioma . Among its related pathways are PIP3 activates AKT signaling and MTOR signalling . WebAmplification of the gene encoding the epidermal growth factor receptor (EGFR) occurs commonly in glioblastoma (GBM), leading to activation of downstream kinases, including phosphatidylinositol 3'-kinase (PI3K), Akt, and mammalian target of rapamycin (mTOR). A serine-threonine kinase, mTOR controls …
RPTOR - My Cancer Genome
WebMar 29, 2024 · RICTOR amplification is a rare but therapeutically relevant genomic alteration across solid tumors. Our results support further pre-clinical and clinical investigation with … WebRPTOR amplification FGFR1 amplification CCND1 amplification MYC amplification EMSY amplification FGF19 amplification FGF3 amplification FGF4 amplification MYST3 amplification ZNF703 amplification BR103 NOTCH1 L2457V; TP53 P151R;ARID2 E71*, S1491*; ESR1 Y537C; GATA3 S411fs*29+; notebooking publisher
Oncobiology and treatment of breast cancer in young women
WebTranslational Cancer Research, Vol 4, No 1 February 2015 41 Translational Cancer Research. ll rights reserve. www.thetcr.org Transl Cancer Res 2015;4(1):40-59 biology discoveries, although our comprehension remains WebRPTOR amplification was specifically enriched in basal and luminal A BRCA in young adults ( Figure 2D). Recent studies have linked RPTOR activity with treatment implications in … WebHome > Life Science Research > Products > PCR Amplification > PrimePCR™ PCR Primers, Assays, and Arrays > Gene: Rptor, Mouse > PrimePCR™ Probe Assay: Rptor, Mouse ... Rptor, Mouse Reaction: 200 x 20 µl reactions Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe ... notebooking examples