Cisplatin electrolyte

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August undefined, 2024

WebMar 1, 2024 · A case of an elderly male presenting with significant recurrent hyponatremia, and prerenal azotemia, with recent exposure to cisplatin along with significant hypovolemia and urinary loss of sodium is reported. Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude … WebFLUID AND ELECTROLYTE 2 Fluid and electrolyte Question one Edema occurs when excessive fluid surrounds the cells of the human body, leading to cellular edema. The fluid may also accumulate in the collagen-mucopolysaccharide, leading to interstitial edema (Cicardi, et al., 2014). Edema is very detriment because it increases the distance of …

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WebElectrolyte disturbances were observed after several days of cisplatin administration including changes in levels of sodium, potassium, phosphorus, calcium, and chloride. Clinical observations also identified CP toxicity. WebNational Center for Biotechnology Information high wooden sandals

Electrolyte imbalances and Cisplatin - Cancer Survivors Network

WebSep 23, 2024 · Background: Cisplatin is an important drug in the treatment of various Cancers. However, this drug causes nephrotoxicity that is linked to electrolyte … WebJan 12, 2024 · Platinum chemotherapy (Cisplatin), is commonly associated with electrolyte imbalances, including low magnesium (up to 90% using Cisplatin), low potassium, low phosphate, low calcium, and low sodium (up to 43%). This is the type of chemo typically used for lung, colon, ovarian, breast, head/neck, bladder, and testicular cancers. WebSep 27, 2024 · Nausea and Vomiting: cisplatin for injection can cause severe nausea and vomiting. Use highly effective antiemetic premedication [see Dosage and Administration ( 2.1) and Warnings and Precautions ( 5.3 )]. • Myelosuppression: cisplatin for injection can cause severe myelosuppression with fatalities due to infections. high wooden shelf garage

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Cisplatin dosing, indications, interactions, adverse effects

WebApparently not. It was probably due to the treatment. Also, prior to every chemo treatment, I was not only hydrated, but was given a giant bag of electrolytes, with potassium, … WebJul 28, 2024 · Cisplatin is a platinum coordination complex chemotherapy used in the treatment of testicular, ovarian cancer, bladder, and lung cancers, as well as other … small ivory corner electric fireplaceWebCharacterizing the impact of magnesium and potassium-supplemented hydration with cisplatin and the subsequent electrolyte replacement requirements Characterizing the impact of magnesium and potassium-supplemented hydration with cisplatin and the subsequent electrolyte replacement requirements high woods yamate

"WebMay 24, 2006 · Conclusion: Cisplatin can cause permanent nephrotoxicity, including Gitelman-like syndrome. This drug should be considered among the possible causes of chronic unexplained electrolyte disorders. Publication types Case Reports Review MeSH terms Adult Alkalosis / chemically induced* Antineoplastic Agents / adverse effects* " - Cisplatin electrolyte

Cisplatin electrolyte

National Center for Biotechnology Information

WebCisplatin (CP) is a remarkably effective Pt-based anticancer drug, but it also exhibits severe toxic side effects, including nephrotoxicity and ototoxicity, and CP nephrotoxicity is a … WebApr 15, 2024 · Additionally, cisplatin-induced nephrotoxicity led to the unmasking of a familial form of hypomagnesemia. ... Previously, the baseline electrolyte profile was normal. He was suspected to have nephrotoxicity complicated by acute hypomagnesaemia. Hence, the boy was treated with supplementation and hypomagnesaemia recovered …

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WebCisplatin 1. NAME 1.1 Substance 1.2 Group 1.3 Synonyms 1.4 Identification Numbers 1.4.1 CAS 1.4.2 Other Numbers 1.5 Brand Names, Trade Names 1.6 Manufacturers, Importers 1.7 Presentation, Formulation 2. SUMMARY 2.1 Main Risks and Target Organs 2.2 Summary of Clinical Effects 2.3 Diagnosis 2.4 First aid measures and management … WebSep 26, 2024 · While generally mild electrolyte deficiencies are pretty benign, moderate/severe abnormalities can cause many life …

WebThe proteinuria associated with cisplatin nephrotoxicity is attributed to a tubular defect. 32 Hemolytic uremic syndrome has also been described, especially when cisplatin is combined with bleomycin. 33 Sequential … WebCisplatin is a coordinate metal complex with significant antineoplastic activity and various effects, including acute anc chronic renal insufficiency and renal magnesium …

WebSep 15, 2024 · Since its approval in 1979 cisplatin has become one of the most extensively used chemotherapeutics in the clinic and although cell resistance and … WebAs cisplatin treatment is clinically associated with diarrhoea and 5-HT is known to be an intestinal secretagogue,16, 17 we investigated the effect of cisplatin on intestinal fluid …

WebCisplatin is a potent antineoplastic agent derived from platinum and commonly used in the treatment of head and neck, bladder, ovarian, and testicular malignanc Cisplatin-Induced Acute Kidney Injury and Renal Salt Wasting Syndrome Federal Practitioner

WebSep 1, 2024 · Cisplatin for injection, USP, a platinum-based drug for intravenous use, is a white to light yellow lyophilized powder. Each vial of Cisplatin for injection, USP … small itx buildWebDec 2, 2014 · Cisplatin is one of the most widely used and highly effective drug for the treatment of various solid tumors; however, it has dose-dependent side effects on the kidney, cochlear, and nerves. Nephrotoxicity is the … high woodside farm consettWebwasting due to cisplatin therapy. Although patients with cancer have hyponatremia due to many etiologies (Table 1), SIADH is the most common etiol-ogy that is directly attributable to cancer. This is because can-cer patients have nonvolume and nonosmotic stimuli for antidiuretichormone(ADH)release,suchasnausea/vomiting high woods sportsmen clubWebApr 12, 2024 · As previously described, also the cisplatin can induce electrolyte imbalances. In this case, the standard approach to avoid cisplatin-induced nephrotoxicity and the consequent electrolyte alteration is the administration of IV isotonic saline solution in order to stimulate the diuresis. Some authors suggest to add 2 gr of magnesium … high woodside farmWebResults: We observed an increase in serum creatinine level to a peak of 1.9 mg/dL (range, 0.8 to 7.8) in the dopamine group, in comparison to 1.4 mg/dL (range, 0.9 to 3.3) in the placebo group (P = .04). Urinary magnesium excretion increased and EGF excretion decreased in both groups. small ivory figurinesWebSep 15, 2024 · Since its approval in 1979 cisplatin has become one of the most extensively used chemotherapeutics in the clinic and although cell resistance and toxicity hinder its efficacy it continues to be a gold standard regimen. Cisplatin's side effects primarily include nephrotoxicity, gastrointestinal toxicity, neurotoxicity and ototoxicity. high wooley equestrianWebJun 8, 2024 · Cisplatin injection can cause dose-related peripheral neuropathy that becomes more severe with repeated courses of the drug. Neurologic symptoms … high woods country park fishing